diff --git a/dll/apisets/CMakeLists.txt b/dll/apisets/CMakeLists.txt
index a08f9f1..348cf2d 100644
--- a/dll/apisets/CMakeLists.txt
+++ b/dll/apisets/CMakeLists.txt
@@ -27,7 +27,7 @@ function (add_apiset apiset_name baseaddress)
     if(NOT MSVC)
         target_compile_options(${apiset_name} PRIVATE -fno-builtin)
     else()
-        target_compile_options(${apiset_name} PRIVATE /wd4026 /wd4273)
+        target_compile_options(${apiset_name} PRIVATE /wd4026 /wd4273 /Oi-)
     endif()
 
     add_importlibs(${apiset_name} ${ARGN} ntdll)
diff --git a/dll/apisets/CMakeLists.txt.in b/dll/apisets/CMakeLists.txt.in
index 12ca868..3ec26d4 100644
--- a/dll/apisets/CMakeLists.txt.in
+++ b/dll/apisets/CMakeLists.txt.in
@@ -27,7 +27,7 @@ function (add_apiset apiset_name baseaddress)
     if(NOT MSVC)
         target_compile_options(${apiset_name} PRIVATE -fno-builtin)
     else()
-        target_compile_options(${apiset_name} PRIVATE /wd4026 /wd4273)
+        target_compile_options(${apiset_name} PRIVATE /wd4026 /wd4273 /Oi-)
     endif()
 
     add_importlibs(${apiset_name} ${ARGN} ntdll)
diff --git a/sdk/lib/drivers/rdbsslib/CMakeLists.txt b/sdk/lib/drivers/rdbsslib/CMakeLists.txt
index 7b6ec54..56ab772 100644
--- a/sdk/lib/drivers/rdbsslib/CMakeLists.txt
+++ b/sdk/lib/drivers/rdbsslib/CMakeLists.txt
@@ -3,6 +3,11 @@ add_definitions(-DUNICODE -D_UNICODE -DRDBSS_TRACKER)
 include_directories(${REACTOS_SOURCE_DIR}/drivers/filesystems/mup
                     ${REACTOS_SOURCE_DIR}/sdk/lib/drivers/copysup)
 
+if(MSVC)
+    # error C4101: 'BreakpointsSave' : unreferenced local variable in Release-Configuration
+    replace_compile_flags("/we4101" " ")
+endif()
+
 list(APPEND SOURCE
     rdbss.c)
 
diff --git a/sdk/lib/rtl/CMakeLists.txt b/sdk/lib/rtl/CMakeLists.txt
index 65bf915..eb76fc9 100644
--- a/sdk/lib/rtl/CMakeLists.txt
+++ b/sdk/lib/rtl/CMakeLists.txt
@@ -5,6 +5,11 @@ add_definitions(
     -D_NTSYSTEM_
     -D_NTDLLBUILD_)
 
+if(MSVC)
+    # error C4101: unreferenced local variable in Release-Configuration due to debug logging
+    replace_compile_flags("/we4101" " ")
+endif()
+
 list(APPEND SOURCE
     access.c
     acl.c
@@ -112,7 +117,8 @@ endif()
 
 add_asm_files(rtl_asm ${ASM_SOURCE})
 add_library(rtl ${SOURCE} ${rtl_asm})
-add_pch(rtl rtl.h SOURCE)
+#disable pch to prevent macro redefinition rtl.h WIN32_NO_STATUS
+#add_pch(rtl rtl.h SOURCE)
 add_dependencies(rtl psdk asm)
 
 list(APPEND SOURCE_VISTA